CBSE Nanopore Project Publications

Nanopore sensors for nucleic acid analysis.
Nakane JJ, Akeson M, Marziali A. J Phys Condensed Matter. 2003 Aug 20; 15(32):R1365-93.

Highly accurate classification of Watson-Crick basepairs on termini of single DNA molecules.
Winters-Hilt S, Vercoutere W, DeGuzman VS, Deamer D, Akeson M, Haussler D. Biophys J. 2003 Feb; 84(2 pt 1):967-76.

Discrimination among individual Watson-Crick base pairs at the termini of single DNA hairpin molecules. Vercoutere WA, Winters-Hilt S, DeGuzman VS, Deamer D, Ridino SE, Rodgers JT, Olsen HE, Marziali A, Akeson M. Nucleic Acids Res. 2003 Feb 15; 31(4):1311-8.

Biosensors for DNA sequence detection.
Vercoutere W, Akeson M. Curr Opin Chem Biol. 2002 Dec; 6(6):816-22.

Characterization of nucleic acids by nanopore analysis.
Deamer DW, Branton D. Acc Chem Res. 2002 Oct; 35(10):817-25.

Evaluation of nanopores as candidates for electronic analyte detection.
Nakane J, Akeson M, Marziali A. Electrophoresis. 2002 Aug; 23(16):2592-601.

Use of a nanoscale pore to read short segments within single polynucleotide molecules.
Akeson M, Deamer DW, Vercoutere W, Braslau R, Olsen H. In: Structure and Dynamics of Confined Polymers, J Kasianowicz, M Kellermayer, D Deamer (eds). Bikal, Hungary, 2002, pp. 187-200.

Mechanism of ionic current blockades during polymer transport through pores of nanometer dimensions. Deamer DW, Olsen H, Akeson MA, Kasianowicz J. In: Structure and Dynamics of Confined Polymers, J Kasianowicz, M Kellermayer, D Deamer (eds). Bikal, Hungary, 2002, pp.165-176.

Rapid discrimination among individual DNA hairpin molecules at single nucleotide resolution using an ion channel. Vercoutere W, Winters-Hilt S, Olsen H, Deamer D, Haussler D, Akeson M. Nat Biotechnol. 2001 Mar; 19(3):248-52.

New DNA sequencing methods.
Marziali A, Akeson M. Annu Rev Biomed Eng. 2001; 3:195-223.

Nanopores and nucleic acids: prospects for ultrarapid sequencing.
Deamer DW, Akeson M. Trends Biotechnol 2000 Apr; 18(4):147-51.

Water transport by the bacterial channel alpha-hemolysin.
Paula S, Akeson M, Deamer D. Biochim BiophysActa. 1999 Apr 14; 1418(1): 117-26.

Microsecond time-scale discrimination among polycytidylic acid, polyadenylic acid, and polyuridylic acid as homopolymers or as segments within single RNA molecules.
Akeson M, Branton D, Kasianowicz JJ, Brandin E, Deamer DW. Biophys J. 1999 Dec; 77(6):3227-33.