The Center for Biomolecular Science & Engineering offers unique opportunities for research, teaching, learning, and satisfying careers in bioinformatics and related fields—a rich working and learning environment at UC Santa Cruz.
We have these open positions:
Research Technician, Haussler laboratory, Howard Hughes Medical Institute
Software Developer (Programmer/Analyst 3)
You can search and apply for additional jobs online at the UCSC Staff Employment web site and the UCSC Academic Employment Opportunities web site.
UCSC is an affirmative action/equal opportunity employer.
We recommend that you include the following in your application: a cover letter describing why you are interested in and qualified for this particular job, a curriculum vita or resume, and your salary history.
Haussler laboratory, UC Santa Cruz, Howard Hughes Medical Institute
Posted 5/14/2013; initial application review 5/28/2013
The Howard Hughes Medical Institute conducts scientific research in laboratories affiliated with leading academic centers throughout the United States. We have an immediate opening for an experienced research technician in the laboratory of Professor David Haussler at the University of California Santa Cruz. The ideal candidate works effectively both independently and in a team and has strength in developing and performing complex stem cell culture and molecular biology procedures and in organizing the laboratory environment.
Research in the Haussler laboratory focuses on two areas: 1) Understanding the role of non-protein-coding regions of the human genome, including those encoding ncRNAs and DNA regulatory elements on the transcriptional programs underlying vertebrate development, using in vitro differentiation of human and primate embryonic stem cells and mouse models to study these processes; 2) Developing cancer cell-line models to mimic specific tumor types based on extensive genome-wide analysis of transcription, genomic alterations, and epigenetic modifications of tumor samples and candidate cell lines; these experiments involve various molecular biology techniques, including high-throughput DNA sequence analysis and mammalian cell culture.
ESSENTIAL FUNCTIONS: Under the general supervision of the lab director, assist in the development and implementation of investigative procedures to accomplish research goals and independently perform scientific investigative procedures, actively contributing to the research results of the laboratory. Analyze and interpret experimental results and assist in determining relevance to lab projects. Prepare reports, charts, and graphs to communicate results at scientific meetings or for manuscripts for publication. Supervise and perform technical and administrative tasks to ensure smooth operations of the research biology laboratory, currently a team of ten.
QUALIFICATIONS include either a Bachelor of Science degree in an appropriate field of science or technology or equivalent in education and experience AND two or more years of related research experience or an advanced degree in an appropriate area of science or technology AND one or more years of related laboratory experience;
experience with mammalian tissue culture techniques, such as cell line maintenance, transfection, and isolation of stable clones; experience with and an understanding of the underlying scientific principles in basic molecular biological techniques, such as DNA manipulation, PCR, RNA work, recombinant protein expression, purification, and immunobiology; operational knowledge of advanced laboratory equipment; demonstrated ability to organize a laboratory environment, maintain equipment, and manage a cell culture facility; demonstrated ability to develop novel or innovative techniques to address research problems; ability to review goals, analyze processes necessary to achieve those goals, and develop techniques and systems required to meet those goals; demonstrated ability to write and prepare clear, concise reports about scientific research projects for various purposes, including publication and presentation at scientific meetings.
RANK: Programmer/Analyst 3
Posted 12/03/2012; initial review date 12/17/2012
The Center for Biomolecular Science & Engineering (CBSE) at UC Santa Cruz seeks an analytical problem-solver to develop software and databases for a major genome analysis resource for biologists. The position is responsible for software development and implementation, constructing and utilizing annotation databases for a variety of genomes, and communicating with our international community of scientific users. The successful candidate must be an experienced engineer who is articulate, able to learn and integrate technical information quickly, and has a strong commitment to quality and best engineering practices. The position requires independence, creativity, and self-motivation in a team environment.
OVERVIEW OF THE ORGANIZATION
The CBSE conducts research in a diverse set of projects at the cutting edge of biomedical research, focusing on high-throughput analysis of the human genome. The UCSC Center for Genomic Sciences, part of the CBSE, is a talented cross-disciplinary team that builds databases and develops software for the widely used UCSC Genome Browser, a tool that facilitates genome analysis and comparison within and across multiple species. The browser provides views of assembled genome sequences that are integrated with details of evolutionary conservation, synteny, genetic map markers, known and predicted genes, SNPs, transcript structure, alternative splicing, and a host of other critical data. It also links to several highly complex sets of data, including those from the Encyclopedia of DNA Elements (ENCODE) project, the 1000 Genomes project, and the UCSC Cancer Genomics Browser. The browser software and data are made available via web servers to thousands of scientists and biomedical researchers worldwide, providing a resource vital to research on the UCSC campus and the larger international scientific community.
ESSENTIAL FUNCTIONS: Under general supervision, the software developer will be responsible for supporting and extending the UCSC Genome Browser database and software and interfacing with collaborators and users.
QUALIFICATIONS include Bachelor’s degree in computer science or equivalent education; extensive experience working with Javascript, C, and CSS; extensive experience working in a UNIX or Linux environment; familiarity with relational database concepts and SQL; experience using a distributed source code revision control system; knowledge of bioinformatics methods and applications